I just gave it a good clean with washing up liquid, warm water and a soft sponge before first use. But after use use the proper Kegland stuff which I believe is just re-branded PBW. But I always give it a good clean with warm soapy water and a soft sponge before hand to get off the stuck on solid matter anyway. Once cleansed I just put 10 ltrrs of water and chemsan in it until the next use.
For the bottom bottle I recommend using the included tool. Also make sure it is fully depressurised before trying to undo things. Also don't be tempted to overtighten things. I gave the left hand thread bit a really good tighten up when I first assembled it, but everything else just gets a bit of a nip up and I've had no issues whatsoever with it leaking liquid or gas. There is no need to really tighten things up that much. I think alot of people probably over tighten these things and that causes problems and can damage seals.
You can use some of that food grade vasoline stuff to lubricate threads and seals and I started out using it, but it just became too much of a faff and no longer bother.
Its a pretty well thought out bit of kit the Fermzilla, but not particularly well executed. I think with a bit of patience and a bit of technique its not a problem and a really good bit of kit!