I haven't run a micro brewery but I have run my own business for six years. Running your own business is very rewarding and beats working for someone else, but before you even go any further do you research big time.
Two things you will need to do is firstly see what the profit will be on a 8bbl (which you are obviously trying to ascertain) and see if it will support two directors secondly can two people operate this size of business or will you need to take on a member of staff. Any staff wages (which will also includes the tax and NI) comes of your bottom line.
The second thing is selling the stuff. It is all well and good having the production capabilities but you need to be able to sell the stuff on a regular basis and at a margin which will support you and your staff. I have been lucky in my business that i have one very good contract which is the main stay of my business, however with the downturn i have had to offer my services (I am a commercial picture framer) else where which is not easy, as a result I employ an agent who takes a commission.
When assessing your costs their are lots of hidden extras that you may not appreciate. Cost of premises will not only include the rent and rates but also may include a service charge. My premises cost me £10000 a year for the rent but this is inflated to over £16000 when you take into account rates, service charge and landlords buildings insurance ( this separate to your your contents insurance and liability insurance). Leases are usually on a three yearly basis in which you will be liable for the rent even if you go bust (most landlords ask for a personal guarantee even if your company is limited). Solicitors will charge £1-2000 and a survey will be needed on the building before you sign the lease as most leases are fully repairing which means you will be liable for the upkeep of the building whilst it is in your care.
I'm not trying to dampen your enthusiasm but running a business is hard. It means getting up everyday and fighting for you business and putting every last drop of energy into it.
To succeed you need to have a great product which will sell, common sense and an awful amount of luck of the good variety. I have seen to many business that have failed because they think that because they have got all the kit their business will be a success. Getting up and running is only the start of it, keeping it going is an art.
If you are serious then plan everything in the minutest detail research your market and do the maths. Take advice from the many government agencies
http://www.businesslink.gov.uk/bdotg/action/layer?topicId=1073858805 and find a good accountant, 40-50K is a lot of money to be playing with, and finally become a limited company, it is the most tax efficient way to earn money.
Good luck
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AG