I think its all sadly inevitable. Any notion that football is anything other than a business went out the window a long time ago and I say that as a lifelong Liverpool fan. What makes football great with all the drama of promotion, relegation, qualifying etc. also makes for a terrible business model. The owners funding these teams (or arranging for their clubs to be saddled with debt) want more stability, I understand why but I don't like it. They are probably doing this as a negotiating tactic again but they know even if the premier league, FA, UEFA and FIFA call their bluff, they are in a strong position. None of the organisations have favoured taking a principled stand over commercial interests before so why would they now? The premier league aren't likely to kick out these 6 clubs. They represent under a third of the league but they feature in over half of all the televised fixtures in the UK, and a massive chunk of the £5billion the league gets from oversees revenues is predicated on these 6 teams. If they did kick them out, there would be a collapse in funding, especially from overseas markets. It would leave the rest of the premier league on more of a level pegging with the EPL, but probably not in a good way. Even if there was a surprising outbreak of scruples in the Premier League, La Liga and Serie A, the appetite for these teams in Asia, America and Africa is vast, regardless of what competition they play in.
The FA are already worried about the FA Cup being devalued by the bigger teams and its problematic for them to sell the tournament without these teams and the teams themselves are increasingly playing lip service to it, so it won't be a drag for them to be kicked out. They would love an excuse to get out of the League Cup too I think. I also doubt FIFA will follow through on banning players from these teams in international tournaments. They have ridiculous amounts of cash in sponsorship from the likes of Adidas, Pepsi etc. And look at the players who feature in adverts as part of these deals, over the past 20 odd years, they have predominantly featured players from the 12 teams who have signed up the ESL. FIFA aren't going to jeopardise those sort of deals by taking these players and teams out of play.
The TLDR version of this is that the domestic, continental and international bodies have created this monster and now it has them by the short and curlies. Very depressing.